Dimitrios Diamantis

I'm an organic chemist with experience in cancer and senescent research. My research focused on the development of diagnostic and theragnostic probes emitting in the near infrared region. During my PhD thesis I developed and evaluated, via a plethora of analytical techniques, 16 diagnostic probes and 2 theragnostic prodrugs that are selectively activated and target tumor microenvironment. These probes exhibited excellent photophysical properties and were used to visualised tumor in vitro and in vivo. During the aforementioned i acquired knowledge on the writing of scientific articles and international patents. Moreover, I gained through knowledge of common purification techniques including HLPC and column chromatography, as well as characterization techniques such as 1D/2D NMR spectroscopy, UV-Vis and fluorescence spectroscopy and MS spectrometry.

1. Research Staff member 

University of Ioannina 

July 2019-July 2020

Main tasks

• Harvesting of plants rich in flavonoids and terpenoids from the region of Epirus and preparation of the aqueous and ethanolic extracts
• Evaluation of the antioxidant activity of the extracts using DPPH and Folin-Ciocalteu assays
• Spectroscopic determination of the total phenolic content in crude extracts via NMR spectroscopy
• Identification and qualification of the major and minor crude extract ingredients utilizing their NMR footprint
   

2. Assistant in the organic chemistry undergraduate laboratory

University of Ioannina 

April 2019-June 2019

Main tasks 

• Scheduling and preparing the students for the experiments as wells as explaining the procedure to them
• Cleaning the laboratory and the equipment before and after the experiments to protect the samples from possible contamination
• Preparation and record of the samples for NMR and IR spectroscopy 
• Ensuring safety in and around the lab by following safety protocols

3. Internship

July 2019-August 2019

Main tasks

• Implementation of daily chemical, microscopic, bacteriological, and physical water quality tests.
• Implementation of precised and accured validation and verifaction of on-line water quality process and control instrumentation used throughout the water treatment process.

4. Assistant in the industrial chemistry undergraduate laboratory

University of Ioannina

July 2018-July 2018

Main tasks

• Scheduling and preparing the students for the experiments as wells as explaining the procedure to them
• Cleaning laboratory and the equipment before and after the experiments to protect the sampels from possible contamination
• Ensuring safety in and around the lab by following safety protocols

5. Research Staff member

University of Ioannina

October 2014- July 2015

Main tasks

• Establishment of a chemical library consisting of: i) isolated phytochemical compounds, ii) anticancer drugs, iii) drug conjugates iv) plant extracts, v) fluorescent dyes and vi) supramolecules
• Performance of extensive and competitive studies utilizating fluorescence spectroscopy and isothermal titration calorimetry to determine the interaction between small ligands and proteins
• Synthesis and characterization of peptides and bioconjugation with a lanthanide-based chromophore

1. September 2017 - July 2022

Doctor of Philosophy in organic chemistry

University of Ioannina, School of Science, Chemistry Department

PhD thesis entitled “Rational design and synthesis of diagnostic and theragnostic probes that emit in the near infrared region and target tumour microenvironment” 

Grade 10/10

2. September 2014 - July 2017

Master of Science in synthetic chemistry, biochemistry - bioactive compounds

University of Ioannina, School of Science, Chemistry Department

MSc thesis entitled “Modification of natural products aiming the enhancement of their bioavaibility”

Grade 9.82/10 

3. October 2010 - September 2014

Bachelor in Chemistry

University of Ioannina, School of Science, Chemistry Department

Grade 7.15/10